Statin muscle-related adverse events. Accessed Oct. Qu H, et al. Effects of coenzyme Q10 on statin-induced myopathy: An updated meta-analysis of randomized controlled trials. Journal of the American Heart Association. Coenzyme Q Natural Medicines. Taylor BA, et al. Statin-associated muscle disease: Advances in diagnosis and management. Coenzyme Q10 CoQ10 : In depth.
National Center for Complementary and Integrative Health. Lopez-Jimenez F expert opinion. Mayo Clinic. See also After a flood, are food and medicines safe to use?
Arcus senilis: A sign of high cholesterol? Birth control pill FAQ Cholesterol concerns? Get moving Cholesterol concerns? Lose excess pounds Cholesterol level: Can it be too low? Cholesterol test kits: Are they accurate? The authors concluded that taking CoQ10 and eating a diet low in saturated fat may help protect against diseases caused by free radical damage.
In another study , older adults received CoQ10 and selenium supplements for 48 months. The participants reported improvements in vitality, physical performance, and overall quality of life.
CoQ10 supplements appear to be safe, and most people tolerate them even at high doses. However, CoQ10 supplements can cause the following side effects:.
People should consult a doctor before taking any new medications or dietary supplements, including CoQ CoQ10 is an antioxidant that exists in almost every cell of the human body. Although the body naturally produces CoQ10, some people may benefit from taking supplements. Overall, CoQ10 supplements appear relatively safe and cause few side effects. Supplements are not regulated by the Food and Drug Administration FDA for purity or verified for labeling accuracy, so purchase only those products that have been tested by an independent lab.
People who are interested in trying CoQ10 supplements may want to consult a healthcare professional first. Experts do not recommend CoQ10 for people taking blood-thinning medications, insulin , or certain chemotherapy drugs.
CoQ10 is available in some drug stores, pharmacies, and online. Mitochondria are often called the powerhouses of the cell. We explain how they got this title, and outline other important roles that they carry out.
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Now let's look at CoQ This coenzyme is needed for energy production within muscle cells. Some studies have shown that statins decrease the concentration of CoQ10 in both muscle tissue and in the bloodstream.
The hypothesis is that, if you decrease the CoQ10 levels, you reduce the production of energy in muscle cells and they won't function as well, leading to muscle aches, weakness or inflammation. In extremely severe cases -- I've seen this in very few of my patients -- statins can lead to the death of muscle cells, and a decrease in muscular CoQ10 may be one of the reasons. Massive cell death can also lead to acute kidney failure, but fortunately, in most cases, after stopping the statin and getting intravenous fluids, the patient's symptoms will quickly improve.
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